Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia.

The effect of lipoprotein apheresis (Direct Adsorption of Lipids, DALI) (LA) on plasma levels of pentraxin 3 (PTX3), an inflammatory marker that reflects coronary plaque vulnerability, and expression of PTX3 mRNA was evaluated in patients with hyperLp(a)lipoproteinemia and angiographically defined atherosclerosis/coronary artery disease. Eleven patients, aged 55 ± 9.3 years …

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Hypercholesterolemia Family “Today we can intervene effectively in children”

“L’ipercolesterolemia familiare – spiega la dottoressa Guardamagna, pediatra dell’Università di Torino – è una condizione ereditaria che si correla con un elevato rischio di eventi cardiovascolari che si manifestano di solito in età adulta, anche se il soggetto non ha in precedenza manifestato sintomi specifici. Diverso il caso dei soggetti …

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